Since the beginning of the year, the National Institutes of Health (NIH) have promoted a research and nutrition program for the identification of dietary patterns.
Precision Health Nutrition or Nutrition for Precision Health, is a program of the NIH Common Fund, promoted through the Investigation programme All of Us. The goal of this program is to develop algorithms that can predict individual responses to foods and dietary patterns.
La nutrición no solo es clave para el desarrollo humano, sino también para la prevención y tratamiento de enfermedades. Aunque la dieta perfecta varía para cada persona, este programa busca apoyarse en las ciencias biomédicas, Artificial Intelligence (AI), investigación del microbioma para generar nueva información sobre la nutrición personalizada o nutrición de precisión.
In this sense, the first Strategic Plan for Nutrition Research of the NIH has also been implemented, which contemplates the investigation of how individual human biology, diet, environmental, social and behavioral factors influence health.
For this, the Nutrition for Precision Health program will use data from All of Us, being the first study that takes advantage of the information generated by said research, to find answers to other scientific questions.
The study has three main objectives:
- Examine observed individual differences in responses to different diets, by studying the interaction between diet, genes, proteins, microbiome, metabolism, and other individual factors.
- Utilizar AI para el desarrollo de algoritmos que puedan predecir respuestas individuales a alimentos y patrones dietéticos.
- Validate algorithms for clinical application.

To carry out this important study, five main components are interconnected:
- In the first place, the Research Coordination Center, whose purpose is the administrative management of all the components involved.
- Next come the Clinical Centers, which are responsible for recruiting, consenting, and enrolling All of Us participants in the nutrition program.
- El tercer componente son los Centros de Generación de Datos, que realizan diversas tareas como:
- a) Perform genetic analyzes of the human gut microbiome;
- b) Perform metabolic analysis;
- c) Advanced dietary assessment methods
- El Centro de Artificial Intelligence, Modelado Multimodal de Datos y Bioinformática, es el cuarto componente y busca establecer modelos matemáticos y computacionales, desarrollar algoritmos y mejorar la visualización de datos.
- Finally, the All of Us Biobank receives, processes, and stores the biosamples and metadata.
The NIH has provided 170 million dollars for the development of this nutrition study and it has been promoted by the Department of Health and Human Services (HHS) and All of Us.
Learn more: https://commonfund.nih.gov/nutritionforprecisionhealth