{"id":9549,"date":"2020-09-07T09:48:34","date_gmt":"2020-09-07T14:48:34","guid":{"rendered":"https:\/\/saluddigital.com\/?p=9549"},"modified":"2025-10-21T14:30:32","modified_gmt":"2025-10-21T20:30:32","slug":"estudio-sugiere-que-el-ultrasonido-dirigido-podria-destruir-el-cancer-sin-danar-las-celulas-sanas","status":"publish","type":"post","link":"https:\/\/saluddigital.com\/en\/avance-de-la-ciencia\/estudio-sugiere-que-el-ultrasonido-dirigido-podria-destruir-el-cancer-sin-danar-las-celulas-sanas\/","title":{"rendered":"Study suggests targeted ultrasound could destroy cancer without damaging healthy cells"},"content":{"rendered":"
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The research was published in Applied Physics Letters.<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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This research was developed by the California Institute of Technology (Caltech), and the Beckman Research Institute at City of Hope, which explores the physical properties of the cells that make up the tumors and thus provide a new treatment. Although this new approach lies in its inset, scientists claim to have developed a low-intensity ultrasound technique that kills cancer cells without damaging healthy cells.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Reducing the intensity of ultrasound, manages to match the frequency with the target cells, according to their study they managed to separate several types of cancer cells without damaging healthy blood cells.<\/p>

\u201cHere, we test the hypothesis that biomechanical differences between cancerous and healthy cell types cause these cells to have different responses to LIPUS, allowing selective ablation of cancer cells with targeted ultrasound waveforms. This hypothesis is predicated on cancer cells' altered cellular\/nuclear morphology, DNA content, nuclear-nucleolar volume ratios, cytoskeletal stiffness, and viscoelastic properties. In computational studies, these differences were predicted to result in the differential response of malignant cells to specific ultrasound parameters when compared to healthy cells.\u201d<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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Through computational studies these differences were predicted for treatment to respond to malignant cells, depending on ultrasound parameters. A cell suspension model was used for them for preliminary testing.\u00a0<\/p>

You can consult the full study through the following link: https:\/\/aip.scitation.org\/doi\/10.1063\/1.5128627<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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\n\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/i><\/span>\n\t\t\t\t\t\t\t\t<\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\tBIBLIOGRAPHY<\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t

AIP<\/strong><\/p>

https:\/\/aip.scitation.org\/doi\/10.1063\/1.5128627<\/a><\/p>

\u00a0<\/strong><\/p>

HEALTH DAY <\/strong><\/p>

https:\/\/consumer.healthday.com\/cancer-information-5\/mis-cancer-news-102\/targeted-ultrasound-destroys-cancer-without-harming-healthy-cells-study-753682.html<\/a><\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

La investigaci\u00f3n fue publicada en la revista Applied Physics Letters. Esta investigaci\u00f3n fue desarrollada por el Instituto Tecnol\u00f3gico de California (Caltech), y el Instituto Beckman de Investigaci\u00f3n en City of Hope, en la cual se exploran propiedades f\u00edsicas de las c\u00e9lulas que conforman los tumores y as\u00ed brindar un nuevo tratamiento. A pesar de que, este nuevo enfoque se encuentra en sus inicios, los cient\u00edficos dicen haber desarrollado una t\u00e9cnica de ultrasonido de baja intensidad que mata c\u00e9lulas cancerosas sin da\u00f1ar las c\u00e9lulas sanas. La reducci\u00f3n de la intensidad del ultrasonido, logra coincidir la frecuencia con las c\u00e9lulas objetivo, seg\u00fan su estudio lograron separar varios tipos de c\u00e9lulas cancerosas sin da\u00f1ar c\u00e9lulas sangu\u00edneas sanas. \u201cAqu\u00ed, probamos la hip\u00f3tesis de que las diferencias biomec\u00e1nicas entre los tipos de c\u00e9lulas cancerosas y sanas hacen que estas c\u00e9lulas tengan diferentes respuestas a LIPUS, lo que permite la ablaci\u00f3n selectiva de c\u00e9lulas cancerosas con formas de onda de ultrasonido dirigidas. Esta hip\u00f3tesis se basa en la morfolog\u00eda celular \/ nuclear alterada, el contenido de ADN, las relaciones de volumen nuclear-nucleolar, la rigidez citoesquel\u00e9tica y las propiedades viscoel\u00e1sticas de las c\u00e9lulas cancerosas\u201d. A trav\u00e9s de estudios computacionales dichas diferencias fueron predichas para que el tratamiento respondiera a las c\u00e9lulas malignas, dependiendo de los par\u00e1metros del ultrasonido. Para ellos se utiliz\u00f3 un modelo de suspensi\u00f3n de c\u00e9lulas para realizar pruebas preliminares.  Puedes consultar el estudio completo a trav\u00e9s del siguiente enlace: https:\/\/aip.scitation.org\/doi\/10.1063\/1.5128627 BIBLIOGRAF\u00cdA AIP https:\/\/aip.scitation.org\/doi\/10.1063\/1.5128627   HEALTH DAY https:\/\/consumer.healthday.com\/cancer-information-5\/mis-cancer-news-102\/targeted-ultrasound-destroys-cancer-without-harming-healthy-cells-study-753682.html<\/p>","protected":false},"author":1,"featured_media":9551,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[152,156,3401,1418],"tags":[145],"class_list":["post-9549","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-avance-de-la-ciencia","category-big-data","category-iotapps","category-resena-de-publicaciones-cientificas","tag-noticias"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/posts\/9549","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/comments?post=9549"}],"version-history":[{"count":0,"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/posts\/9549\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/media\/9551"}],"wp:attachment":[{"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/media?parent=9549"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/categories?post=9549"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/tags?post=9549"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}