{"id":9336,"date":"2020-08-26T09:16:28","date_gmt":"2020-08-26T14:16:28","guid":{"rendered":"https:\/\/saluddigital.com\/?p=9336"},"modified":"2025-10-21T14:34:19","modified_gmt":"2025-10-21T20:34:19","slug":"estudio-utiliza-machine-learning-para-conocer-como-el-cerebro-codifica-recuerdos-a-corto-plazo","status":"publish","type":"post","link":"https:\/\/saluddigital.com\/en\/avance-de-la-ciencia\/estudio-utiliza-machine-learning-para-conocer-como-el-cerebro-codifica-recuerdos-a-corto-plazo\/","title":{"rendered":"Study uses machine learning to know how short-term memories are coded in the brain x"},"content":{"rendered":"
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The study was published on November 1, 2019 in Nature Communications.<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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Researchers from the N.1 Institute of Health at the National University of Singapore (NUS) conducted a study on working memory<\/em> or working memory, which is the enable to manipulate information in the short term. \u201cMemory maintenance appears to involve the sustained activity of neurons in the lateral prefrontal cortex (LPFC)\u201d.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Researchers in their hypothesis claim that memory maintenance seems to involve the activity of neurons in the lateral prefrontal cortex so memory maintenance seems to involve sustained activity of neurons in the lateral prefrontal cortex.<\/p>

Researchers developed an optimization algorithm, through which they found a low-dimensional subspace containing invariant memory information over time. This information was reduced in trials where two adult monkeys were used, and both made errors in the assigned task, and was also found in trial periods that were not used to find subspace.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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Scientists, led by Assistant Professor Camilo Libedinsky of the NUS Department of Psychology, and Titular Professor Shih-Cheng Yen of the Innovation and Design Program at the NUS School of Engineering, found that a population of neurons in the frontal brain lobe contains short-term stable memory information within dynamically changing neural activity.<\/p>

For the realization of this study, two adult monkeys were trained to perform a task with an intermediate distractor. A total of 256 LPFC neurons and 137 FEF neurons were recorded. \u201cThe LPFC has a high number of neurons with mixed-selective responses, which dramatically increase the dimensionality of representations, and may support reliable information transmition.\u201d<\/p>

The study showed that a region below the LPFC could read invariant memory information over time using subspace, however, it has not been shown that any region uses subspace to read information. Through machine<\/em> learning<\/em> scientists demonstrated that it is possible to find stable information within the changing code of the neural population.<\/p>

Now researchers are expanding such studies to learn how different regions of the brain interact in the processing of received information.<\/p>

\u00a0<\/p>

To read the full study, go to the following link: https:\/\/www.nature.com\/articles\/s41467-019-12841-y#Sec7<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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\n\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/i><\/span>\n\t\t\t\t\t\t\t\t<\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\tBIBLIOGRAPHY<\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t

NATURE<\/strong><\/p>

https:\/\/www.nature.com\/articles\/s41467-019-12841-y#Sec7<\/a><\/p>

\u00a0<\/p>

NUS <\/strong><\/p>

https:\/\/news.nus.edu.sg\/research\/using-machine-learning-tools-reveal-how-memories-are-coded-brain<\/a><\/p>

\u00a0<\/p>

FCS HEALTH<\/strong><\/p>

https:\/\/salud.carlosslim.org\/descubren-aspecto-clave-sobre-como-el-cerebro-codifica-los-recuerdos-a-corto-plazo\/<\/a><\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

El estudio fue publicado el 1 de noviembre de 2019 en Nature Communications. Investigadores del Instituto de Salud N.1 de la Universidad Nacional de Singapur (NUS) realizaron estudio sobre sobre working memory o memoria de trabajo, que es la habilitad de manipular informaci\u00f3n en corto plazo. \u201cEl mantenimiento de la memoria parece implicar la actividad sostenida de las neuronas en la corteza prefrontal lateral\u201d mencionan al inicio del estudio. Los investigadores en su hip\u00f3tesis aseguran que el mantenimiento de la memoria parece implicar la actividad de neuronas en la corteza prefrontal lateral por lo que el mantenimiento de la memoria parece implicar la actividad sostenida de las neuronas en la corteza prefrontal lateral (LPFC). Los investigadores desarrollaron un algoritmo de optimizaci\u00f3n, a trav\u00e9s de este encontraron un subespacio de baja dimensi\u00f3n que contiene informaci\u00f3n de memoria invariante en el tiempo. Esta informaci\u00f3n se redujo en los ensayos donde se utilizaron dos monos adultos, y ambos cometieron errores en la tarea asignada, y tambi\u00e9n se encontr\u00f3 en per\u00edodos del ensayo que no se utilizaron para encontrar el subespacio. Los cient\u00edficos, liderados por el Profesor Asistente Camilo Libedinsky, del Departamento de Psicolog\u00eda de la NUS, y el Profesor titular Shih-Cheng Yen, del Programa de Innovaci\u00f3n y Dise\u00f1o en la Facultad de Ingenier\u00eda de la NUS, encontraron que una poblaci\u00f3n de neuronas en el l\u00f3bulo frontal del cerebro contiene informaci\u00f3n de memoria estable a corto plazo dentro de la actividad neuronal que cambia din\u00e1micamente. Para la realizaci\u00f3n de este estudio se entrenaron dos monos adultos para realizar una tarea con un distractor intermedio. Se registraron un total de 256 neuronas LPFC y 137 neuronas FEF. \u201cEl LPFC tiene un gran n\u00famero de neuronas con respuestas selectivas mixtas, que aumentan dr\u00e1sticamente la dimensionalidad de las representaciones y pueden soportar una transmisi\u00f3n de informaci\u00f3n fiable\u201d. En el estudio se demostr\u00f3 que una regi\u00f3n abajo del LPFC podr\u00eda leer informaci\u00f3n de memoria invariante en el tiempo utilizando el subespacio, no obstante, no se ha demostrado que alguna regi\u00f3n utilice el subespacio para leer informaci\u00f3n. A trav\u00e9s de herramientas de machine learning los cient\u00edficos demostraron que es posible encontrar informaci\u00f3n estable dentro del c\u00f3digo cambiante de la poblaci\u00f3n neuronal. Ahora los investigadores est\u00e1n ampliando este tipo de estudios para conocer como interact\u00faan las diferentes regiones del cerebro en el procesamiento de la informaci\u00f3n recibida. Para leer el estudio completo (en ingl\u00e9s) ingresa al siguiente enlace: https:\/\/www.nature.com\/articles\/s41467-019-12841-y#Sec7 BIBLIOGRAF\u00cdA NATURE https:\/\/www.nature.com\/articles\/s41467-019-12841-y#Sec7 NUS https:\/\/news.nus.edu.sg\/research\/using-machine-learning-tools-reveal-how-memories-are-coded-brain SALUD FCS https:\/\/salud.carlosslim.org\/descubren-aspecto-clave-sobre-como-el-cerebro-codifica-los-recuerdos-a-corto-plazo\/<\/p>","protected":false},"author":1,"featured_media":9337,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3399,152,156,1418],"tags":[145],"class_list":["post-9336","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ai-analitica","category-avance-de-la-ciencia","category-big-data","category-resena-de-publicaciones-cientificas","tag-noticias"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/posts\/9336","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/comments?post=9336"}],"version-history":[{"count":0,"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/posts\/9336\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/media\/9337"}],"wp:attachment":[{"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/media?parent=9336"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/categories?post=9336"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/tags?post=9336"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}