{"id":9209,"date":"2020-08-20T09:29:17","date_gmt":"2020-08-20T14:29:17","guid":{"rendered":"https:\/\/saluddigital.com\/?p=9209"},"modified":"2025-10-21T14:35:01","modified_gmt":"2025-10-21T20:35:01","slug":"cientificos-reconstruyen-tejido-de-la-traquea-a-traves-de-bioimpresion-3d","status":"publish","type":"post","link":"https:\/\/saluddigital.com\/en\/avance-de-la-ciencia\/cientificos-reconstruyen-tejido-de-la-traquea-a-traves-de-bioimpresion-3d\/","title":{"rendered":"Scientists rebuild trachea tissue through \"3D bioprinting\""},"content":{"rendered":"
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Scientists at Wake Forest Institute Regenerative Medicine (WFIRM), in the United States used 3D printing for the reconstruction of a trachea tissue and cartilage.<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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After previous attempts at bioprinting tracheal constructions, positive results were finally obtained. In the process of this project, different research approaches were developed, combining three technologies: patient-specific medical images, hydrogels and polymerics that function as imitators of biomechanical properties.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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\u201cPeople have tried other materials, but the problem has been they were using just one material that is not strong enough to hold the airways open and does not provide the flexibility needed. Our bioprinting method provides a combination of flexibility and strength needed to mimic native tracheal tissue\u201d explained PhD Sean Murphy, lead author and assistant professor of regenerative medicine at WFIRM.<\/p>

The success of the approach used in this study was due to the incorporation of softer hydrogels containing stem cells into the pores of printed tracheal structures.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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Despite a preliminary study, Anthony Atala, director of WFIRM and also co-author of research, is confident that regenerative medicine treatments will be used in the future to completely replace tracheal areas affected by disease or even accidents. The next steps in our research would be to evaluate the long-term function, to ensure proper tissue formation and strength retention,\" he explains.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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\n\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/i><\/span>\n\t\t\t\t\t\t\t\t<\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\tBIBLIOGRAPHY<\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t

SCIENCE DAILY<\/strong><\/p>

https:\/\/www.sciencedaily.com\/releases\/2019\/12\/191204144855.htm<\/a><\/p>

\u00a0<\/p>

HEALTH CARLOS SLIM FOUNDATION<\/strong><\/p>

https:\/\/salud.carlosslim.org\/por-primera-vez-cientificos-realizan-bioimpresion-3d-del-tejido-de-la-traquea\/<\/a><\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

Cient\u00edficos del Wake Forest Institute Regenerative Medicine (WFIRM), en Estados Unidos utilizaron impresi\u00f3n 3D para la reconstrucci\u00f3n de un tejido de la tr\u00e1quea y diferentes cart\u00edlagos. Luego de intentos previos de bioimpresi\u00f3n de construcciones traqueales, finalmente se obtuvieron resultados positivos.\u00a0 En el proceso de este proyecto se tuvieron distintos enfoques de investigaci\u00f3n, se combinaron tres tecnolog\u00edas: im\u00e1genes m\u00e9dicas espec\u00edficas de paciente, hidrogeles y polim\u00e9ricos que funcionan como imitadores de propiedades biomec\u00e1nicas. \u201cLa gente hab\u00eda probado otros materiales, pero el problema fue que utilizaron un material que no era lo suficientemente fuerte como para mantener abiertas las v\u00edas respiratorias y no aportaba la flexibilidad necesaria. Nuestro m\u00e9todo de bioimpresi\u00f3n brinda una combinaci\u00f3n de flexibilidad y resistencia necesaria para imitar a los tejidos traqueales nativos\u201d, explic\u00f3 el Dr. Sean Murphy, autor principal y profesor asistente de medicina regenerativa en el WFIRM. El \u00e9xito del enfoque utilizado en este estudio se debi\u00f3 a la incorporaci\u00f3n de hidrogeles m\u00e1s blandos que contuvieran las c\u00e9lulas madre en los poros de las estructuras traqueales impresas. A pesar de tratarse de un estudio preliminar, Anthony Atala, director del WFIRM y tambi\u00e9n coautor de la investigaci\u00f3n, conf\u00eda que en un futuro se podr\u00e1n aprovechar los tratamientos de medicina regenerativa para reemplazar enteramente zonas traqueales afectadas por enfermedades o incluso accidentes. Los siguientes pasos en nuestra investigaci\u00f3n ser\u00edan evaluar la funci\u00f3n a largo plazo, para garantizar la formaci\u00f3n adecuada de tejido y la retenci\u00f3n de la fuerza\u201d, explica. BIBLIOGRAF\u00cdA SCIENCE DAILY https:\/\/www.sciencedaily.com\/releases\/2019\/12\/191204144855.htm \u00a0 SALUD FUNDACI\u00d3N CARLOS SLIM https:\/\/salud.carlosslim.org\/por-primera-vez-cientificos-realizan-bioimpresion-3d-del-tejido-de-la-traquea\/<\/p>","protected":false},"author":1,"featured_media":9210,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[152,156],"tags":[145],"class_list":["post-9209","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-avance-de-la-ciencia","category-big-data","tag-noticias"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/posts\/9209","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/comments?post=9209"}],"version-history":[{"count":0,"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/posts\/9209\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/media\/9210"}],"wp:attachment":[{"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/media?parent=9209"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/categories?post=9209"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/tags?post=9209"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}