{"id":15462,"date":"2021-05-27T09:40:45","date_gmt":"2021-05-27T14:40:45","guid":{"rendered":"https:\/\/saluddigital.com\/?p=15462"},"modified":"2025-10-21T12:39:58","modified_gmt":"2025-10-21T18:39:58","slug":"wearables-para-la-adherencia-terapeutica-en-salud-conductual","status":"publish","type":"post","link":"https:\/\/saluddigital.com\/en\/big-data\/wearables-para-la-adherencia-terapeutica-en-salud-conductual\/","title":{"rendered":"Wearables for therapeutic adherence in behavioral health"},"content":{"rendered":"
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The problem of lack of adherence to treatment in patients with mental illness, has been approached through the use of wearables and has also provided solutions.<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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Lack of adherence to treatment leads to non-adherence to medication, and in addition to affecting other patients, can lead to an increase in healthcare costs. In the United States, only one in three patients with schizophrenia adheres to their medication regimen, and this lack of adherence subsequently translates into re-hospitalization costs.<\/p>

In the United States, the Food and Drug Administration approved digital aripiprazole, an antipsychotic medication that contains an ingestible sensor to control and track consumption. In this way it was possible to find and provide support to patients with less adherence, however, its high price, 85 times more than generic aripiprazole, makes it far from being a solution for now.<\/p>

This year a study<\/a> was published in Nature, on the medication of psychiatric patients and how through activity patterns it is possible to know the adherence of each patient. The study details how through an accelerometer and an electrocardiogram incorporated in a digital medicine system of a wearable <\/em>or a patch, records of medication intake are obtained and thus know the patient's activity and whether there are behavioral changes directly related to the patient's adherence.<\/p>

In that study 95 patients with schizophrenia, bipolar disorder and major depressive disorder, all on stable doses of aripiprazole, received a supply of digital aripiprazole for several weeks.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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The digital aripiprazole sensors were able to provide an objective measure within parameters of medication adherence. The data collected by the sensor was used to determine how well heart rate and accelerometer data could predict adherence.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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\u201cThe accelerometers in each patch allowed investigators to calculate an \u201cactivity rhythm score\u201d capturing how consistent a person\u2019s step count was from day-to-day. They also calculated a \u201crelative active-interval heart rate\u201d which indicated the intensity of physical activity. Both a high activity rhythm score (indicating that a person\u2019s step count was consistent with their routine), and a high relative active-interval heart rate (indicating intense physical activity as compared to baseline), were correlated with the likelihood that a study participant would take their medications the next day\u201d, explained in their editorial in the journal Nature.<\/p>

In this way data on high activity rate (such as step count) were associated with greater adherence than those with lower activity rate.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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\n\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/i><\/span>\n\t\t\t\t\t\t\t\t<\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t BIBLIOGRAPHY<\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t

NATURE<\/strong><\/p>

https:\/\/www.nature.com\/articles\/s41746-021-00458-9<\/a><\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

El problema de la falta de adherencia al tratamiento en pacientes con enfermedades mentales, ha sido abordado mediante el uso de wearables y adem\u00e1s ha aportado soluciones La falta de adherencia al tratamiento provoca el incumplimiento de la medicaci\u00f3n, y adem\u00e1s de afectar a los dem\u00e1s pacientes, puede llegar a generar un aumento de costos de atenci\u00f3n m\u00e9dica. En Estados Unidos solo uno de cada tres pacientes con esquizofrenia logra adherencia a su r\u00e9gimen de medicaci\u00f3n, esta falta de cumplimiento posteriormente se traduce en costros de rehospitalizaci\u00f3n. En Estados Unidos la Administraci\u00f3n de Alimentos y Medicamentos, aprob\u00f3 el aripiprazol digital, un medicamento antipsic\u00f3tico que contiene un sensor ingerible para controlar y hacer un seguimiento del consumo. De esta forma se pudieron encontrar y brindar apoyo a los pacientes con menos adherencia, no obstante, por su alto precio, de 85 veces m\u00e1s que el aripiprazol gen\u00e9rico lo sit\u00faa lejos de ser una soluci\u00f3n por ahora. Este a\u00f1o fue publicado un estudio en Nature, sobre la medicaci\u00f3n de pacientes psiqui\u00e1tricos y c\u00f3mo a trav\u00e9s de patrones de actividad es posible conocer la adherencia de cada paciente. El estudio detalla c\u00f3mo a trav\u00e9s de un aceler\u00f3metro y un electrocardiograma incorporado en un sistema de medicina digital de un wearable o un parche, se obtienen registros de la ingesti\u00f3n de medicamentos y conocer as\u00ed la actividad del paciente y conocer si existen cambios de comportamiento directamente relacionados a la adherencia del paciente. En dicho estudio 95 pacientes con esquizofrenia, trastorno bipolar y trastorno depresivo mayor, todos con dosis estables de aripiprazol, recibieron un suministro de aripiprazol digital durante varias semanas. Los sensores digitales de aripiprazol lograron proporcionar una medida objetiva dentro de los par\u00e1metros de la adherencia a la medicaci\u00f3n. Los datos recolectados por el sensor se utilizaron para determinar qu\u00e9 tan bien la frecuencia card\u00edaca y los datos del aceler\u00f3metro pod\u00edan predecir la adherencia. \u201cLos aceler\u00f3metros de cada parche permitieron a los investigadores calcular una \u2018puntuaci\u00f3n de ritmo de actividad\u2019 que capturaba la consistencia del recuento de pasos de una persona d\u00eda a d\u00eda. Tambi\u00e9n calcularon una \u2018frecuencia card\u00edaca relativa de intervalo activo\u2019 que indicaba la intensidad de la actividad f\u00edsica. Tanto una puntuaci\u00f3n de ritmo de actividad alta (que indica que el recuento de pasos de una persona era consistente con su rutina) y una frecuencia card\u00edaca de intervalo activo relativa alta (que indica actividad f\u00edsica intensa en comparaci\u00f3n con la l\u00ednea de base), se correlacionaron con la probabilidad de que un participante del estudio tomar sus medicamentos al d\u00eda siguiente\u201d, explican Leia Wedlund y Joseph Kvedar en su editorial en la revista Nature. De esta forma los datos sobre alto ritmo de actividad (como el conteo de pasos) se relacionaron con una mayor adherencia que aquellos con menor ritmo de actividad. BIBLIOGRAF\u00cdA NATURE https:\/\/www.nature.com\/articles\/s41746-021-00458-9<\/p>","protected":false},"author":1,"featured_media":15463,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[156],"tags":[145],"class_list":["post-15462","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-big-data","tag-noticias"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/posts\/15462","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/comments?post=15462"}],"version-history":[{"count":0,"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/posts\/15462\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/media\/15463"}],"wp:attachment":[{"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/media?parent=15462"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/categories?post=15462"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/tags?post=15462"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}