{"id":13433,"date":"2021-04-12T10:05:14","date_gmt":"2021-04-12T15:05:14","guid":{"rendered":"https:\/\/saluddigital.com\/?p=13433"},"modified":"2025-10-21T12:50:06","modified_gmt":"2025-10-21T18:50:06","slug":"inteligencia-artificial-y-analisis-de-sangre-para-detectar-tempranamente-enfermedad-de-alzheimer","status":"publish","type":"post","link":"https:\/\/saluddigital.com\/en\/resena-de-publicaciones-cientificas\/inteligencia-artificial-y-analisis-de-sangre-para-detectar-tempranamente-enfermedad-de-alzheimer\/","title":{"rendered":"Artificial Intelligence and blood tests for an early detection of Alzheimer's disease"},"content":{"rendered":"
\n\t\t\t\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t

Through blood tests and the use of Artificial Intelligence (AI), it is possible to detect Alzheimer's disease at an early stage.<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t

In March of this year, the study \u201cThrough blood tests and the use of Artificial Intelligence (AI), it is possible to detect Alzheimer's disease at an early stage\u201d was published in the journal PLOS ONE. In the study the researchers explain that \u201cwe evaluated the utility of leucocyte epigenomic-biomarkers for Alzheimer\u2019s Disease (AD) detection and elucidates its molecular pathogeneses.\u201d<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

\n\t\t\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\"\"\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t

For this purpose, the researchers used six different AI methods, such as deep learning and others. Through AI they were able to evaluate epigenomic biomarkers of leukocytes in blood. In this way they found more than 150 genetic differences among the study participants, between the two groups, participants with AD and participants without AD.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

\n\t\t\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t\t\t

Deep learning was the most effective AI platform, as the assessment of no cytosine-phosphate-guanines (CpG) achieved a sensitivity and specificity rate of 97%.<\/p>

Lead author Ray Bahado-Singh, chair of the Department of Obstetrics and Gynecology at Oakland University, explained, \u201cIt\u2019s almost as if the leukocytes have become a newspaper to tell us,'This is what is going on in the brain',\u201d The researchers take the discovery with caution, but point out that if the findings can be replicated, they may help in the early diagnosis of AD.<\/p>

\u201cThe holy grail is to identify patients in the preclinical stage so effective early interventions, including new medications, can be studied and ultimately used,\u201d said Bahado-Singh.<\/p>

On the other hand, Khaled Imam, MD, director of geriatric medicine at Beaumont Health and co-investigator of the study, explained, \u201cHaving biomarkers in the blood, and being able to identify AD years before symptoms start, hopefully we\u2019d be able to intervene early on in the process of the disease.\u201d<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

\n\t\t\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t
\n\t\t\t\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/i><\/span>\n\t\t\t\t\t\t\t\t<\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t BIBLIOGRAPHY<\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t

AI MEAS<\/strong><\/p>

https:\/\/ai-med.io\/more-news\/ai-and-simple-blood-test-may-flag-early-stage-alzheimers\/<\/a><\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

A trav\u00e9s de an\u00e1lisis de sangre y la utilizaci\u00f3n de Inteligencia Artificial (IA), es posible detectar la enfermedad de Alzheimer en etapa temprana. En marzo de este a\u00f1o, fue publicado el estudio “Inteligencia artificial y epigen\u00f3mica leucocitaria: evaluaci\u00f3n y predicci\u00f3n de la enfermedad de Alzheimer de aparici\u00f3n tard\u00eda”, en la revista PLOS ONE. En el estudio los investigadores explican que \u201cevaluamos la utilidad de los biomarcadores epigen\u00f3micos leucocitarios para la detecci\u00f3n de la enfermedad de Alzheimer (EA) y dilucidamos su patog\u00e9nesis molecular”. Para esto, los investigadores utilizaron seis m\u00e9todos distintos de IA, como aprendizaje profundo y otros. A trav\u00e9s de IA pudieron evaluar los biomarcadores epigen\u00f3micos de leucocitos en sangre. De esta forma encontraron m\u00e1s de 150 diferencias gen\u00e9ticas entre los participantes del estudio, entre los dos grupos, los participantes con EA y los participantes que no tienen EA. El aprendizaje profundo, fue la plataforma de IA m\u00e1s efectiva, pues la evaluaci\u00f3n de no tienen citosina-fosfato-guaninas (CpG), logr\u00f3 una tasa de sensibilidad y especificidad de 97%. El autor principal Ray Bahado-Singh presidente del Departamento de Obstetricia y Ginecolog\u00eda de la Universidad de Oakland, explic\u00f3 lo siguiente: \u201cEs casi como si los leucocitos se hubieran convertido en un peri\u00f3dico que nos dijera: ‘Esto es lo que est\u00e1 pasando en el cerebro’\u201d. Los investigadores toman con mesura el descubrimiento, pero se\u00f1alan de que poder replicarse los hallazgos encontrados, pueden apoyar en el diagn\u00f3stico temprano de EA. \u201cEl santo grial es identificar a los pacientes en la etapa precl\u00ednica para que las intervenciones tempranas efectivas, incluidos los nuevos medicamentos, se puedan estudiar y, en \u00faltima instancia, utilizar\u201d, dijo Bahado-Singh. Por otra parte, Khaled Imam, MD, director de medicina geri\u00e1trica de Beaumont Health y coinvestigador del estudio, explic\u00f3 que: \u201cTener biomarcadores en la sangre y ser capaces de identificar EA a\u00f1os antes de que comiencen los s\u00edntomas, es de esperar que podamos intervenir temprano en el proceso de la enfermedad\u201d. BIBLIOGRAF\u00cdA AI MED https:\/\/ai-med.io\/more-news\/ai-and-simple-blood-test-may-flag-early-stage-alzheimers\/<\/p>","protected":false},"author":1,"featured_media":13434,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3400,3393,1418,3396],"tags":[145],"class_list":["post-13433","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-diagnostico","category-inteligencia-artificial-y-ciencia","category-resena-de-publicaciones-cientificas","category-uso-de-plataformas-digitales","tag-noticias"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/posts\/13433","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/comments?post=13433"}],"version-history":[{"count":0,"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/posts\/13433\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/media\/13434"}],"wp:attachment":[{"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/media?parent=13433"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/categories?post=13433"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/saluddigital.com\/en\/wp-json\/wp\/v2\/tags?post=13433"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}